Stellenbeschreibung
Join one of Germanys leading research environments for infection biology and immunology. At the Center for Integrative Infectious Disease Research (CIID), University Hospital Heidelberg, you will work at the interface of virology, immunology, tissue engineering, and microfluidics. As part of the Excellence Cluster SynthImmune and a DFG-funded research project, you will contribute to the development of innovative human lymphoid organ models to investigate HIV pathogenesis and immune responses.
You will benefit from state-of-the-art research infrastructure, interdisciplinary collaboration, and excellent opportunities for scientific and professional development.
Your Tasks
You will develop and optimize human lymphoid organ culture models, including tonsil explants and aggregate cultures, to investigate adaptive immune responses and HIV-1 pathogenesis
Using tissue engineering and microfluidic approaches, you will establish next-generation ex vivo lymphoid models with improved longevity, immune competence, and suitability for long-term HIV infection studies
Your work will focus on enabling the investigation of viral persistence and the establishment of HIV latency in human tissue-based model systems
You will apply these models to study the mechanisms of action of the HIV pathogenesis factor Nef and its impact on host immune functions
In collaboration with interdisciplinary research teams, you will examine the anti-HIV activity of neutrophils and their role in antiviral immune responses
Furthermore, you will evaluate de novo immune responses to novel vaccine candidates developed within the Excellence Cluster SynthImmune
You will analyze and present scientific data, contribute to publications in international journals, and actively participate in collaborative research activities within the project network
Your Profile
Masters degree in Immunology, Biology, Biochemistry, Molecular Life Sciences, or a related field
Solid background in immunology and a strong interest in infection biology and translational research
Experience with primary human immune cell culture and/or organoid or tissue-based model systems is an advantage
Practical expertise in flow cytometry is desirable
Excellent English communication skills, both written and spoken
Genuine scientific curiosity and enthusiasm for interdisciplinary research
A collaborative, proactive, and well-organized working style rounds off your profile
About us
For further information, please contact Kathrin Bajak by phone at +49 6221 56-5061 or via email .
Advance innovative HIV research with us!
We look forward to receiving your online application.
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