Stellenbeschreibung
Primary Duties & Responsibilities:
Make key contributions to the ERC Starting Grant funded project “PerturbPhos” (Grant agreement ID: 101222284), developing ultra-sensitive mass spectrometry (MS)-based phosphoproteomics technologies to study how drugs affect a patients tumor proteome
Build and optimize a scalable phosphoproteomics platform tailored to high-dimensional perturbation experiments of primary cells
Analyze large-scale (phospho)proteomics datasets using R or Python-based computational tools to integrate prior knowledge and characterize drug-induced phosphorylation changes
Work and communicate efficiently across inter-professional teams
Disseminate project results through presentations and manuscripts.
Required Skills & Qualifications:
PhD in (bio)chemistry, molecular biology, systems biology, or a related field
Theoretical knowledge and practical skills in mass spectrometry-based proteomics, ideally with hands-on experience in low-input phosphoproteomics
Demonstrated experience with mammalian cell culture and sample preparation for MS analysis
Ability to independently develop and troubleshoot MS-based proteomics workflows
Prior experience with clinical patient material and/or characterizing small molecule drugs is desired
Proficiency in R or Python for analyzing omics datasets, including statistical analysis and integration of multiple datatypes
Strong track record of scientific excellence (e.g., high-quality first-author publications), rigorous research practice, and commitment to research integrity
Strong ability work and communicate effectively in interdisciplinary teams (clinicians, biologists, bioinformaticians)
Strong scientific writing and presentation skills in English.
We offer you even more:
Classification is based on TV-L in pay grade E13 if the personal and collective agreement requirements are met.
Reference number: DM20/2026
Limited to 24 months, with an option to extend
Regardless of origin, age, gender or disability - you are welcome here at Jena University Hospital.
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